Nutrayours Artemisinin Helps Promote General Health

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About this item
100% NATURAL PRODUCT: No artificial colors or flavors Verified herb identity, confirmed highest quality of raw herb and the extract Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards Third-party lab tested, pure Artemisinin Artemisinin, has been for over two millennia, one of the most common herbs prescribed in traditional Chinese medicine (TCM)(1).
Artemisinin acts in a multi-specific manner also against hematological malignancies. The chemical structure of Artemisinin is a sesquiterpene lactone, which contains an endoperoxide bridge essential for activity. The main mechanism of action of Artemisinin and its derivatives(artesunate, dihydroartemisinin, artemether) toward leukemia, multiple myeloma, and lymphoma cells comprises oxidative stress response, inhibition of proliferation, induction of various types of cell death as apoptosis, autophagy, ferroptosis, inhibition of angiogenesis, and signal transducers, as NF-κB, MYC, amongst others.
Many in vivo experiments in disease-relevant animal models demonstrate therapeutic efficacy of artemisinin-type drugs against rheumatic diseases (rheumatoid arthritis, osteoarthritis, lupus erythematosus, arthrosis, and gout), lung diseases (asthma, acute lung injury, and pulmonary fibrosis), neurological diseases (autoimmune encephalitis, Alzheimer's disease, and myasthenia gravis), skin diseases (dermatitis, rosacea, and psoriasis), inflammatory bowel disease, and other inflammatory and autoimmune diseases.
Keywords: Artemisia annua L.; Artemisinin; Artesunate;

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Specifications

Results

Test Methods

Physical and Chemical
Loss on Drying	≤ 10.0%	Conforms	GB 5009.3
Residue on Ignition	≤ 6.0%	Conforms	GB 5009.4
Mesh Size	95% pass 80 mesh	Conforms	CP2020
Appearance	Green to brown powder	Conforms	Visual
Odor & Taste	Characteristic	Conforms	Organoleptic

Contaminants
Arsenic (As)	≤ 0.50 mg/kg	0.276 mg/kg	ICP-MS||GB 5009.268
Lead (Pb)	≤ 2.00 mg/kg	1.070 mg/kg	ICP-MS||GB 5009.268
Mercury (Hg)	≤ 0.05 mg/kg	0.011 mg/kg	ICP-MS||GB 5009.268
Cadmium(Cd)	≤ 0.50 mg/kg	0.153 mg/kg	ICP-MS||GB 5009.268

Microbiological
Total Plate Count	≤ 1,000 cfu/g	Conforms	GB 4789.2
Mold&Yeast	≤ 100 cfu/g	<10 cfu/g	GB 4789.15
E. Coli	<10 cfu/g	Conforms	GB 4789.38
Salmonella	Absent/25g	Conforms	GB4789.4
Staphylococcus aureus	<10 cfu/g	Conforms	GB4789.10

Package	Inside package: Double food grade plastic bags(N.W.: 5KG, 25KG). Outside package: Cartons/fiber drums.
Storage	Stored in a well-closed container away from light, heat and moisture
Shelf Life	3 years if sealed and stored under the recommended conditions

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* The statements in this section have not been evaluated by the FDA or EFSA.
References
1. Mancuso RI, Foglio MA, Olalla Saad ST. Artemisinin-type drugs for the treatment of hematological malignancies. Cancer Chemother Pharmacol. 2021;87(1):1-22. doi:10.1007/s00280-020-04170-5 2. Kiani BH, Kayani WK, Khayam AU, Dilshad E, Ismail H, Mirza B. Artemisinin and its derivatives: a promising cancer therapy. Mol Biol Rep. 2020;47(8):6321-6336. doi:10.1007/s11033-020-05669-z
3. Efferth T, Oesch F. The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases. Med Res Rev. 2021;41(6):3023-3061. doi:10.1002/med.21842
4. Tong X, Chen L, He SJ, Zuo JP. Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms. Acta Pharmacol Sin. 2022;43(12):3055-3061. doi:10.1038/s41401-022-00978-4

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